Founded by the pioneers of computer assisted cognitive-behavioral therapy (CCBT), MindStreet is a digital therapeutics company that develops and distributes clinically validated patient programs used by clinicians to effectively and efficiently treat a range of mental health conditions.

Why | Access

We exist to make mental health treatments accessible, affordable and stigma free.

How | Resilience

We make cognitive behavior therapy (CBT) easy to understand and apply to manage symptoms of mental health disorders.

What | DTx

We develop clinically validated, evidence-based digital programs that are 10x more efficient but are as effective as traditional therapy


Valerie (Ramirez) Mukherjee

Founder, Executive Chair

Val is a former Wall Street and Silicon Valley executive turned entrepreneur. A first-generation, low-income college student, raised by a single mother, she transformed her life through education and self-funded her way through Berkeley, Columbia, and Wharton. She later worked at several preeminent technology and finance firms before starting her own investment firm. Growing up in a poor, crime-ridden Bay area neighborhood, she experienced firsthand the trauma of unrecognized, undiagnosed, and untreated mental health disorders within family and friends. She drives MindStreet’s “Netflix of Mental Health,” vision to make mental health programs accessible, affordable, and stigma-free. Val is a nationally ranked tennis player and was a first-time nominee for US Congress. She lives in the greater Seattle area with her husband of 20 years and two teenage children.

Brian Mayhugh

Brian Mayhugh, PhD


Dr. Brian Mayhugh is a licensed clinician and healthcare executive with over 30 years of experience in the behavioral health, employee assistance, and managed care industry. He has designed, built, and launched several digital products, protocols, tools, processes, and benefit programs that covered over 8 million lives 38,000 clients, and 25,000 network providers. His clinical experience includes treating outpatient, hospital, and residential patients and crisis management. Prior to his current role, Dr. Mayhugh has served as Chief Medical Officer, Chief Clinical Officer, Chief Compliance and Privacy Officer, overseeing executive, clinical, provider, compliance, and operations teams at public (Nasdaq) and PE/VC funded private companies. Brian is a keen sailor and clay shooter and lives in Newport Beach, CA with his wife of 30+ years and has two grown sons.


Sumit Bando


Sumit brings deep technology and startup experience to MindStreet. He wrote his first programs in Fortran in 1978, then dove into hardware and microcode before resurfacing to the comfort of higher-level languages. He has been on the Internet since 1981. He started his professional career in 1984 at AT&T Bell Labs, the original Mecca for computer scientists. He holds bachelor's degree and master’s degrees in computer science from IIT Kharagpur and the University of Rochester, respectively, and has worked at four pioneering technology companies with Class A internet addresses. A musician, golfer, and long-time Marin County resident, Sumit is married to a globe-trotting psychiatrist and splits his time between the US and India.


Arvind Murthy


Arvind Murthy is a serial entrepreneur and product developer. His domain expertise and interest lie at the intersection of design, media, and the built environment. He has founded and been a part of several successful startups and led product, business, and marketing teams across various industries, including healthtech, fintech, consumer, retail, and social media. He is a co-director of FoundersBoost the LA ecosystem's preeminent startup pre-accelerator. Arvind is recently married and lives with his wife in Irvine, CA.


Dr. Jesse Wright, M.D., Ph.D.

Co-Founder & Chair, Advisory Board

Dr. Wright is a world-renowned pioneer in the development of digital behavioral health tools. He was the principal author of the first multimedia computer program for psychotherapy and led the production and validation of the Good Days Ahead (GDA) program for depression and anxiety. Over the past two decades, GDA has been extensively studied and clinically validated with over $6 million of grant support from the National Institutes of Health.


S. Brian Mukherjee


Brian is the Founder and Managing Partner of Harmonic Equity, a venture equity firm that provides capital, resources, and mentorship to rapidly scale aspiring technology companies. An engineer and operator turned investor, he has served as Chairman, Director, CEO, and Executive at several public (NASDAQ, LSE) and private, VC/PE-backed companies. Brian led over a dozen companies in the adtech, martech, healthtech, SaaS, data and marketplaces/exchanges through hyper growth, transformations, turnarounds, and exits during his career.


Samuel L. Mayhugh, Ph.D.


Dr. Mayhugh is a trained psychologist with over 40 years of practice and executive leadership of behavioral health companies. His career includes successful innovations in hospital and outpatient behavioral healthcare delivery and benefits management. He was the founder and served as CEO and Chief Clinical Officer of Integrated Behavioral Health a leading managed behavioral health company for over 30 years before it was acquired.